Dental implants have helped millions of men and women enjoy greater confidence, improved facial aesthetics and better oral function following tooth loss. And for the vast majority of patients, the implant process is straightforward and uneventful, with no serious side effects or complications.
But in very few cases, patients may have allergic reactions to the titanium metal used in dental implants. In past blog posts, we’ve discussed the possible complications and risks associated with mercury amalgam fillings and the pros and cons of zirconia implants compared to titanium implants to help you become more aware and informed. In this post, we delve a little deeper into titanium allergies so you can understand how to assess your risk for allergic reaction and feel more confident about your oral health care. Here’s what you should know.
How common are titanium allergies?
Titanium allergies are rare, occurring in about 0.6% of the population, according to one study. That means as many as 1.8 million people in the U.S. may be allergic to titanium to some degree. Other studies suggest the allergic reaction or hypersensitivity to titanium could be much higher. When they do occur, titanium allergy symptoms can range from mild to severe and can include:
- loosening of the implants (or implant failure)
- rash or hives
- sores and swelling in the soft tissues of the mouth
- chronic inflammation in the gums around the implant
- problems with wound healing
- chronic fatigue syndrome
- acne-like swelling or inflammation of the face
- muscle and joint achiness
- neurological problems
Even though the risk of titanium allergy may be quite low, the reactions can have significant impacts on your overall health and wellness -- which brings us to the next issue: How can you tell if you’re allergic to titanium?
Titanium Allergy Test
Many allergies can be diagnosed through a simple method called a skin patch test. In these tests, suspected allergens are applied to very small areas of skin, usually on your back. Then these areas are covered with waterproof bandages and left alone for a period of time. When the time elapses, the skin areas are evaluated for signs of irritation that indicate an allergic reaction.
But while skin patch tests are ideal for some types of allergies, they’re not very accurate for other, including titanium allergies. To test for a titanium allergy, you’ll need to have a different type of test called MELISA (which is short for (Memory Lymphocyte Immunostimulation Assay). MELISA uses a small sample of your blood to check for titanium sensitivity. During the assay, your white blood cells are isolated from the rest of your blood, then exposed to titanium. Over several days, your blood sample is evaluated for signs of allergic reaction. MELISA offers far more accurate results that traditional skin patch allergy tests, especially for applications where the metal will come in contact with bone and soft tissues. In fact, in addition to its use in dentistry, it’s also used to test for metal allergies prior to joint replacement surgery, and it’s used in other industries where metal allergies are a concern. The table below shows some of the metal allergies that can be evaluated using MELISA. IMPORTANT: HELM NEJAD STANLEY DOES NOT ADMINISTER THE MELISA TEST AND THE PATIENT MUST CONTACT THE COMPANY IN GERMANY ON THEIR OWN.
Chart presents stimulation index of tested metals.
- Gold - 1
- Cobalt - 3
- Chromium - 4
- Palladdium - 10
- Titanium - 6
- Tin - 8
- Nickel - 27
- Cadmium - 10
- Phenyl mercury - 5
- Inorganic mercury - 12
(Photo Courtesy of MELISA.org)
First chart presents MELISA reactivity in a 54-yer-old man before and after removal of Ti-based dental implants and screws. Numbers represents stimulation index.
- Ti: before - 70, after - 1
- Ni: before - 8, after - 2
- Pt: before - 6, after - 0.5
- Cd: before - 3, after - 0
- In: before - 2.5, after - 0
- Be: before - 1, after - 0
- Pd: before - 1, after - 0
- Au: before - 1, after - 0
- Cu: before - 0.5, after - 0
- Pb: before - 0.25, after - 0
Second chart presents MELISA reactivity in a 14-yer-old girl before and after removal of Ti-based brackets. Numbers represents stimulation index.
- Ti: before - 8.5, after - 1.5
- Ni: before - 2, after - 1.5
- Pt: before - 1, after - 1.1
- Cd: before - 2, after - 1.7
- In: before - 0.5, after - 0.5
- Be: before - 1, after - 0.85
- Pd: before - 2, after - 1.9
- Au: before - 1, after - 0.8
- Cu: before - 2, after - 1.8
- Pb: before - 0.75, after - 0.25
How accurate is MELISA?
MELISA can be far more accurate than skin patch tests because MELISA shows how the metal will react when it comes in contact with blood and tissue inside your body rather than just the surface of the skin. Still, there have been some studies that question the accuracy and reliability of the test.
In one study from 2016, 57% of patients who claimed an allergy to titanium reacted to other metals, including nickel. This is especially concerning since even the purest titanium contains a trace amount of nickel. And that means if you have an allergy to nickel, you may have an allergic reaction to dental implants that use the metal. Nickel allergies are extremely common; in fact, after poison ivy, they’re the most common cause of allergic skin rashes. Moreover, MELISA has not been completely accepted as 100% reliable by the medical or research communities, which means you’re more or less left on your own to decide if you feel confident in the results of your test prior to receiving implants. As a result, many patients -- even those with no known titanium allergies -- opt for other alternatives to replace their missing teeth in order to avoid the possible risks associated with titanium allergic reactions.
Zirconia Dental Implants: An Alternative to Titanium
So what if your test shows you are allergic to titanium? Does that mean you have to forego implants in favor of a denture or bridge? No. For patients who test positive for titanium allergy, zirconia dental implants could be a good solution. Zirconia is made primarily of ceramic rather than titanium. As a result, you won’t have to worry about allergic reactions. Why aren't zirconia dental implants used all the time? Well, in part because they lack some of the features of titanium implants, like a two-part design and attachment features that help keep the implant especially stable. As detailed in our earlier blog post, zirconia implants still have their pros and cons, but for patients who are allergic to titanium but still want the benefits of an implant, they can be a good choice.
Bridges: Another Option for Tooth Replacement
Of course, implants are not the only solution for replacing a lost tooth. For decades, people have relied on bridges to literally “bridge” the gap left by a missing tooth, and for many patients, a bridge can be a great option. A traditional bridge (shown below) features one or more artificial teeth or "pontics" supported by the teeth on either side of the gap. Before the bridge is placed, these teeth need to receive crowns to hold the tooth and allow normal forces on the artificial tooth to be supported by the neighboring teeth. That means a considerable amount of tooth material will need to be removed from these teeth to “make room” for the crowns. Once the material is removed, these teeth are at increased risks of complications such as root canals, fractures, and recurrent decay. However, bridges have a long and successful track record in helping restore function and aesthetics following tooth loss, and they can be a great choice for many patients.
A Maryland bridge features a slightly different design and attachment process that eliminates the need to remove surface material from the healthy neighboring teeth. Instead, the bridge is secured in place with an adhesive resin to attach the bridge to one or both teeth on either side, often times with little to no tooth removal. This eliminates some of the risks of traditional bridges. Maryland bridges are an especially good option of replacing front teeth in the “aesthetic zone.” However, the bonding application that’s used means these bridges are not nearly as durable as a traditional bridge, and that means the forces exerted during biting and chewing can lead to fractures or debonding of the artificial tooth (pontic). These bridges, while an attractive option for some, are really only meant for aesthetic enhancement, and not as a functional replacement for a missing tooth.
Partial Dentures
Another time-tested option for replacing one or more missing teeth, a partial denture is removable and rests on your gums in the gap left by the missing tooth or teeth. Partial dentures are usually less expensive than other options, but many people don’t want a device that’s removable or poses a risk of slipping, nor do they want to have to remove the denture at night while they’re sleeping. What’s more, the partial denture has a rigid metal framework for strength and stability which unfortunately can often be seen in certain areas and may be intolerable by some patients due to allergy or sensitivity. There are some options for all-plastic dentures, but they tend not to be as functional as a traditional denture with a metal framework. No matter which option you select, it’s estimated that removable partial dentures have at most 25% of the function of a real tooth, implant, or bridge.
Titanium Allergy: The Bottom Line
Allergic reactions to titanium are very rare, but they are a possibility. Before having an implant procedure, it’s a good idea to consider the MELISA test to check for a titanium allergy so you can avoid the resulting side effects. And if you are allergic to titanium or if you suspect you may be, schedule a visit to discuss your other options that can help you restore your teeth and maintain your healthy-looking smile. Call our office at 310-278-0440 and schedule a consultation today.
References:
- Fage et. al. Contact Dermatitis. 2016 Jun;74(6):323-45.
- Muller et. al. Neuro Endocrinol Lett. 2006 Dec;27 Suppl 1:31-5.
I have had many implants done over the years with no problems. For the last few years I have had preparation by dental surgeons, such as removing good teeth, through the advise of my dentist so that he can make a few more implants and many bridges to attach them to. I don’t know what the bridges are composed to, but now I am having severe pain (such as you would have after a burn) around in the inner part of my mouth and also my tongue. It is very difficult to eat and almost nothing has any taste. I think I have dry mouth but don’t think that condition can cause that much pain. Talked to my doctor about dry mouth but I don’t think dry mouth could that bad of a reaction and what I use for that doesn’t help with the burning in my mouth. Appreciate any advise. Thank you!
I had implants about 2 months ago and I’m planning on getting them removed. One has been removed and the other 2
have been covered. I am experiencing itchy wrists and extreme anxiety. I don’t want to suffer for years. I also have Invisaligns, I have been waring for 18 months.
I had dental implants placed back in Aug 2014 on teeth #7 & #10, I was missing these teeth congenitally, therefore, my dentist decided to make room for implants. I noticed after having them placed, my bones felt weak and I started having random muscle weakness and my skin became more sensitive to everything, I would sometimes become really itchy all the time. It was nothing too unbearable, however, I did feel off about this since I hadn’t had these symptoms before. Fast forward to May 2020, I started getting very bad migraines and was diagnosed with status migraines (intractable migraine) in May 2020 then in April 2021 – each time was able to break the cycle with Prednisone. Now, in April 2022, I also had another episode, however, this time I am stuck in this migraine, nothing has helped (ex. Prednisone, SoluMedrol, DHE, etc..) Also — my migraines do not follow the typical pattern of “one-sided pain” mine are focused right in the middle of my forehead above the bridge of the nose (right above where the implants are..) which is another odd anomaly.
I know you aren’t a neurologist, but my question is could these **progressing** symptoms be related to any allergy with my implants? I’m thinking more so Nickel than Titanium, since my ears always reacted to cheap jewelry and seems that TiO2 is not a huge allergen. I do get sharp pains from time to time where my implants are but they go away within minutes, weird?? I do have bleeding gums and think I’m headed for gingivitis, regardless of how much I floss/ brush my teeth.
Can patients slowly develop allergies over time to their implants?
Phew – I know that was a lot but any help or comments would be appreciated. I was a healthy 29 yo and now I’m basically on disability and trying to figure out what the hell is going on with my body.
I had all my teeth taken out and implants put in bottom was good for 8 weeks teeth never fit right got red swollen and blisters on inside cheeks almost cleared with oral rinse then daughter got married and had to put top teeth in that night and next day my cheeks were burning and soars came back 6 weeks later soars still here mind you I still have no teeth so a lot of recitation when I talk and eat they think I was allergic to teeth did a biopsy it came back fine
I’m going thru same thing. 😟 I can’t speak, I can’t figure out the best option for me. What have you decided to do? I had a reaction to zirconium as well. My teeth.. always took care of them. I had two implants with no problem. Three months into the full mouth process, things have changed drastically. Don’t know what to do. Probably do MELISA test…sigh…
I had 2 dental implant lower left about a year ago. Since the implant I started with full ear sensation. ENT didn’t find anything. As time went on it became worst. Canker sore on same side of tongue, irritation to the throat. I saw almost every doctor you can think of. No one can’t find the issue. The dentist remove the crown and post to see if I was allergic to crown or post material. But the irritation is getting worst . I took a mental patch test and nickel came back high. Titanium was non allergic. Should I remove the implant? I didn’t have any issues until I received the implants. Thanks
Dr. Nejad,
My patient has a Straumann Monopure 2 piece zirconia implant. She claims to be allergic to all metals????? My lab tech says he could only do Titanium abutment with a Zirconia crown, and the screw is metal as well. He did speak with the Straumann rep which said as well that only Tt abutment could be done. How likely could she have a reaction? The lab tech and the rep say as long as it’s contained and sealed with the crown there should be no problem.
But my patient has never had a test to make sure she is truely allergic.
I would review this with the patient. There are systems that avoid metal altogether which would have been preferable, but this is still less exposure and something you should inform the patient about and let them decide how to proceed.
I too believe I am having an allergic reaction to all 8 implants. They all failed all at once. Which is very weird. I have chronic fatigue, developed fibromyalgia, having issues thinking and remembering. I also have a lot of medical issues that prevent bone loss due to early menopause pause. I have high blood pressure, taking depression meds and a few other meds that hinder bone growth. Is it the oral surgeons responsibility to check these things out and do an allergy test? I had mine put in 2015 and now all 8 have failed. I have no idea what the heck to do. Does anyone here have any advice? I am going tomorrow for a MELISA test a labcor. You will need to have your doctor write an order for you to go so you can use your insurance. Does anyone have any advice as to why all 8 have failed suddenly at the same time?
Hi Sharon. Firstly, I am sorry you are going through this and I sincerely feel for you. It is not anyone’s job/requirement to do an allergy test. The MELISSA test is a hypersensitivity test (not allergy) and despite how many people you see commenting here, the rate of complications with implants is extremely low worldwide. I don’t disagree that it would be nice if it were done or at least offered so I know what you mean, but I just want to clarify it is not the standard of care. Its impossible to know why they all failed, but any condition that affects bone remodeling could contribute to this. Some conditions that complicate implant success include diabetes (compromised wound healing), osteoporosis, & bisphosphonate use. Social habits such as smoking can also contribute. None of these conditions contraindicates implants, but they do increase the possibility of complications. Have you asked the Oral Surgeon why this happened? That would be the first place, then the second would be a second opinion from an Oral Surgeon or Periodontist. Was it one of those one-day implant clinics by any chance? Best – MN
I had the skin test for titanium allergies. It showed negative,but, I still have severe itchiness! Where do I have the melisa test? I know I have it and have for two years since hip surgery.
Claudia Millis
[email protected]
Please help.
Go to your medical doctor and ask him or her to write an order for a MELISA test and take it to a local labcor. That way you can use your insurance to help pay for the test. I hope this helps.
Hi Sharon- Can you provide a link or any additional information. MELISA requires a specific test kit, sent rapidly back to Melisa in Germany. I have contacted Quest and LabCorp in the past and they said they will not order the kit or take patient-provided kits so that makes it almost impossible. Additionally, it needs to be sent out extremely rapidly to be accepted because it needs to arrive in Germany within 48-hours. Can you please keep me posted if the test is accepted/successful? It would be extremely helpful for the readers of this article and I would include that information in the blog post. Would you also please give me the contact for your local LabCorp so I can contact them and ask some questions, please? The ones here were not willing to do the test, and if they are now that is very useful for everyone. Thank you! Best- MN
Hello. Are you still answering questions? Thank you!
Hi Carolyn- When time permits. It’s hard to manage with my work schedule these days and youtube. Best -MN
Hello Dr. Matt. I currently have 10 dental implants and had them all done within approx. 2 to 3 years and that was over 8 years ago. Let me clarify this by saying that I did have 11 up until November 12th, 2021. I had to get the #14 completely removed due to a horrific infection around the implant site and major unexplained bone loss as well. The pain was and is off the charts. I currently have 6 more implants on left and 4 on lower right. Through the past 3-1/2 years I have been ill with various symptoms including the biggest one being pain on left side of my head. I now see a Neurologist and this has not helped one bit. More recently, I am having problems with swelling on left side of upper arm and breast, extremely high blood pressure, vascular vein problems and much pain in my legs and a huge problem with my intestinal tract. Severe constipation and more. I am feeling defeated and feel that I am being labeled as a hypochondriac in the medical world. Depression and Anxiety have taken a hold of my life and I am not sure what to do next.
Hi Carolyn- I am very sorry to hear that. It is a frustrating situation for sure. There isn’t much data on this and most providers don’t know what to do and/or think it is psychological. In some cases it is psychological but I believe there is more to it. The reality is that most people are completely fine with it, but not everyone reacts the same so anything is possible. The problem is that removing them is pretty invasive and it’s not something to jump to unless there are no other options. I don’t remove implants personally, but if I was doing it, I would be crystal clear that there is NO guarantee that this improves any of your symptoms because it is impossible to be positive they arise from the implant. If that is a risk you are willing to accept, then removing them might be the only option left. What happens if things don’t change after though? There are a lot of possibilities and the body is so complex. It’s something II really wish was easier to manage. Best- MN
I’m feeling your pain. Have so many of same issues, my whole mouth is affected adversely by implants. Wish I had never gone this route.
After I had locator implants done, I developed “ibs” which I have now had several surgeries including a foot of intestine removed. Is it possible that the IBS-like symptoms are the result of titanium implants?
Hey Tom,
I think I’m going through something similar.
I got a tooth implant about 9 years ago. Ever since I’ve had digestive issues – IBS. I did take multiple rounds of antibiotics during the procedures which is linked to creating IBS.
I’m wondering if there is a possibility of the metal in the implant leading to metal toxicity in the body. Which can be linked to IBS and an immune response. I plan to take a test to see what my metal levels are.
Just want you to know you’re not alone. It’s hard to navigate and IBS is tough.
– Malia
Kimberly, I’m terribly sorry you’re having to listen to this Moron. I have also read all the same literature you have undoubtedly read. And Yes you are exactly right. It does say neurological issues which do include Anxiety , Depression and insomnia. If you actually look back and read all of these Dentist (and yes I use the term extremely loosely) advice and opinions, both of them say and insinuate that there is no possible way any of us can have Titanium Hypersensitivity (Titanium allergy). But yet we all just read it before we scroll down to the Brilliant Dentist we have that are saying they have never heard of such a thing. Well I underwent 3 back surgeries because my surgeon kept telling me that NO ONE EVER rejects a cadaver ( clean human) bone. So they opened me up 3 different times and that little cadaver bone was just floating around in my spine and never connected to my body. So on the 3rd operation the surgeon removed it (and lo and behold like I had never mentioned it) and informed me that my body had rejected the cadaver bone. Said like he had suspected and known the entire time that it was going to happen. The problem with the Doctors and Dentists is they went to Medical School and think their intelligence is so damn superior to ours. Us ignorant and uneducated common people. But what they seem to not understand is that we live and have occupied the vessels we call our bodies. Therefore no one knows them better than we do! So when something is off or out of kilter with our bodies we know it, feel it and are acutely aware something is definitely wrong. So please don’t I don’t give up! You know something is not right right right with your body. So I hope you go and find a true professional that will take you seriously and help you with what’s going on with you and your body. God Bless you and I hope only the best for you!
I am terribly sorry you need to call me a moron for being open and honest. I said I am not aware of any connections. People like you make me not want to share and provide this information openly. I could just as easily not put this content out. You might not be aware that I do not place implants, I have no actual preference whether you place implants, and I am personally fine if you decide to remove them. I have no hidden agenda and I do this to open up a conversation. There is really no need for you to be so rude and condescending, it’s disappointing really.
I clearly stated what the “neurological problems” were referencing. I have seen at least 10,000 patients who do not have anxiety, insomnia, or depression from implants and I can say that none have ever made that connection. I can NOT say it’s impossible that it does cause any of those conditions but it is certainly not common and there is no scientific study to make the causal association. It sounds like you absolutely know best though and what do I (moron) know anyway.
Well, I do know this… What happens if you remove an implant and the problem in question does not go away? I know the patient isn’t happy, and the medical provider isn’t happy either. I have seen patients acknowledge that treatment may not improve their condition during the informed consent process, yet still become disappointed or angry when a procedure does not cure their problem. Naturally, that makes many providers extremely hesitant to do whatever a patient says or promise results that are not easily proven or scientifically supported. If you know anything about the body at all, you know that it is complex enough that it would be nearly impossible to pinpoint the cause of a particular condition down to an implant with absolute certainty. I have patients with IBS and dementia who do not have implants or root canals. My GF has IBS and she doesn’t even have a single dental procedure. There are many different reasons people have different conditions and many medical conditions are multi-factorial. My only goal is to provide the information I know and I am sorry you feel the need to be so disrespectful but I wish you the best anyway. I am sure you would be an excellent medical professional and there is nothing stoping you from doing so.
interested in titanium allergy test
My mother has had numerous procedures on her mouth. One or two bridges, crowns, too many to count. Over the past year or so, (since her last dental bridge was put in) she has experienced swelling of her gums, profuse bleeding of the same area, severe weight loss secondary to having her sense of taste and smell being WAY off and not being able to eat-at all. (She has to drink Ensure shakes to maintain herself these days. She also has patches of itchy skin primarily on her back that come and go. I feel she’s been experiencing mental status changes since all of this has been going on as well. I’ve sent her to every doctor we know of. ENT specialists, primary care, neurology, you name it. She’s had scans and testing to rule out everything under the sun. Negative-everything. What I find amusing is her dentist as well, (like so many others mentioned in people’s comments) say it’s “uncommon” and “unrelated” to have it be anything to do with the work they did or the “implants, bridges,” or whatever they’ve done for people to have reactions/issues from it. It looks like even you experts keep telling person after person it’s “probably not” related because it’s “so rare” but IS IT??? Under the same breath, you also say that the majority of things/implants put in patients mouths, “don’t list EXACTLY” what’s in these foreign objects being placed in patients mouths/bodies??? How is this possible? Then, after spending $20, $30 thousand dollars. The dentist just says….??????? Crickets. I would like answers from someone, and someone to figure out what’s wrong with my mother. It’s her mouth. But we are left to try and figure things out on our own. Where do I take her next?
It seems like many people have issues with titanium implants. I mysteriously developed urticaria after first two implants 20 yrs ago and never made the connection. I got two more implants two years ago and it was the start of feeling completely unhealthy. Being tested now, but regardless, I am convinced I am toxic and plan to have all four removed.
Can you have dental implants taken out after 4 years if you are allergic and experiencing terrible symptoms like depression, sleepless nights, fatigue, loss of appetite? My friend has had the Melisa test and is allergic to nickel and is going through constant hell. She won’t go back to the place where she had the implants because she has had a bad experience in the first place. Her two front teeth have also chipped so it has not been worth her pain, money or time. Please could you advise if the implants can be removed after such a long period because I understand they fuse to the bone. Thank you
Hi Liz, They can be removed but it’s not necessarily straightforward depending on the specifics. I would see a specialist to consult about options. Best- MN
Is a gold metal implant potentially better than a titanium one? do you offer or recommend gold as an alternative to titanium?
Gold is not an option for implant materials. Early studes showed it was not possible to get osseointegration around gold (establish soft tissue/cell-free interfaces).
hello all, here is my question to you and the team.
I am post testicular cancer, is there any risk associated with me wanting to get a dental implant? Are there any implications with the use of a titanium implant?
I have no known allergies except to rag weed pollen.
Thanks
Hello, there are no risks I am aware of, but it would be a good idea to have a full evaluation and consult with your treating physicians. Best- MN
Thank you for your reply but the above states there can be neurological problems if you have a titanium allergy. Would this not include anxiety? If not what neurological problems can arrise from a titanium allergy. Also for the MElisa test my doctor can not seen to find where to order this even when i showed him the website. Is there a place with easier access for him to go and order?
As I mentioned, I am not aware of anyone reporting anxiety and I explained that anything is possible but I have not seen anyone make this connection. If you are looking for strong evidence to make that link, you simply will not find it. If you have any references, please send my way. The only I could find is related to Titanium dioxide nanoparticles injected into rats but that’s not very comparable. The more common (but still rare) neurological problem patients report is chronic pain and discomfort, phantom pain, shooting pain, etc.
I have had the MELISA test and positive for some of it’s components. My knee replacement is ceramic but I have a titanium holding it on. Iuse to have dental implants to hold my dentures in place, but had to have them removed about 3 yrs after. I have chronic fatigue and much more. I would give anything to have ceramic teeth implants but of course I can’t afford them. Wondered if you need a person to use as a life changing procedure for your practice? I would be great full and more than happy to show the world how youchanged my life. Thankyou
Can dental implants cause anxiety or neurological issues like ALS? I had one placed and I developed extreme anxiety afterwards and it has been going on for a year. Never had anxiety before and its extreme now to the point I am getting random twitching as well from the anxiety. Is this possible? Also what is the removal process? Mine is a 7mm ultra wide implant and I want it out but scared of the removal.
Hi Kimberly- There is no documented evidence of neurological issues like ALX or anxiety. I suppose anything is possible and if you read around on the internet, you will find some similar encounters but really what matters is to answer your question that there is no way to know for sure or accurately diagnose that. You could have it removed but its a pretty invasive process. They can be very difficult to remove requiring troughing around the implant, but it may be possible to unwind it depending on the details. I would recommend you have a consultation with a periodontist or oral surgeon if you want to explore this option but I just want to emphasize that this would be trial and error so make sure you are ok with that.
I’ve had 5 surgeries on my knee how can I find out if I’m allergic to the implant – I am trying to save my leg
Thank you
Linda
[email protected]
To the dental implant or the knee implant?
Hi Kimberly, yes there is documented research re anxiety being linked to implants! Really recommend you watch ‘Root Cause’ Directed by Frazier Bailey. Informative, fact based and shocking. I am looking to have my titanium implants removed. Good luck and be well soon x
False. There is no documented research. ‘Root Cause’ is not research. I have no problem with removing your implants if you believe this may help, but I have a big problem with incorrect information being labeled research. It is ok to have an opinion, but it is not ok to pass it off as research. To meet the threshold of research, you would need random groups of participants, split into two groups, followed over years to determine cause or association. No such research exists and it is unfortunate that people don’t realize the difference between research and opinion. It should be very clear that a large portion of the population has titanium implants without anxiety, so if anything, there is evidence more likely to indicate the opposite. Best- MN
Could a 3D CT scan result in dizziness, imbalance & ringing in ears?( tinnitis)
Hi Sue- Not that I am aware of. They are reported to have no immediate side effects and I have not had any patients experience this. All the Best- MN
Hello dr stanley
I have 11 implants which have been in for 12 years all are fine apart from one which is in the botton jaw at the lower back.for whatever reason i get agitation next to the implant been looked at and am told nothing is wrong have lived with this since 3 months after being put in im thinking of having it removed.
Hi Steven,
If you have a bunch of implants and none are causing problems, then you definitely aren’t allergic to the one. However, if the one on the lower jaw is causing you pain, there may be some infection or excess cement there that is bothering you. Also, it could be close to the nerve or not fully integrated. A 3D CT scan could give you some more information on what to do. Please keep us posted if you find out.
Thanks!
Dr. Stanley
I just had an extraction of my 3rd molar and I am considering titanium implant as my best replacement option. I am worry I could be allergic to some metals since sometimes I have rashes when I wear watches, some metal necklaces or earrings, not sure if it could have a relationship for titanium implant. I research about the Melissa test and it seems hard to do it now since the Coronavirus the clinic close to me stopped doing it and the test is only diagnostic in Germany which is difficult with the shipping situation now. What other options are available?? Is the patch test as efficient as Melissa test (is easier to get than Melissa but could just be a waster of money??) Thanks
Hi Alexandra, First of all, I would almost always refrain from replacing a third molar with an implant. I don’t know the exact condition of your mouth but this is really not necessary 99% of the time. With that said, in my opinion, none of the tests are completely reliable but any information is better than no information when you have concerns like you do. If you don’t need an implant for the third molar, hopefully, that would be the simplest solution for your predicament. Otherwise, I would go with a patch test or see an allergist for sensitivity testing. All the Best-MN
Hi I had an implant in January ever since I have had metal taste with glen that’s hard to get out. My ears plugged and hurt. Very tired. Some strange things never had before. My dentist assures me it’s not the implant it looks good and in place. My concern I’m having metal reactions. How difficult is it to remove after almost 4 months. I do not have the tooth in yet.
Hi Jan,
Depends where the implant is and how well it has integrated, but it is most likely possible. I would get another opinion if you don’t feel like your concerns are addressed. Keep in mind that if the implant is removed, and your symptoms persist, then you will still need to determine the cause of your symptoms. Its best to evaluate all possibilities before resorting to removing the implant, but if that is your ultimate goal, then I would get an opinion sooner to explore the process. Best- MN
Thank you I appreciate your opinion. I no had no systems before this. I have chronic fatigue syndrome And have worked hard and have had under control by taking good care of myself. I will take your advise and way all options first. My concern if removed how much of a problem is it. I am getting a second opinion. I do value yours also. Thank you so much.
I had two dental implants put in January 13th. Around February 18th My scalp started to itch right behind one ear. It gradually spread over most of my scalp, and then to various other places on the trunk of my body, elbows, arm and a little on top of my hand. Once it moved to my bodyand and I could see it, it is defininitely a rash, and it keeps moving from place to place. No rash on face, no problems in mouth. Dermatologists have been trying to solve problem and gave me a script for a ton of lab tests. As I was leaving office yesterday, nurse stopped me and said, the doctor just told me to ask you if you’ve had any dental work in last six months. I said “as a matter of fact, yes….”. By the time I got home nurse had called and left a message that I should contact my oral surgeon asap – that I might have a titanium allergy. Haven’t called yet, today is Saturday. What do you think? Should I get tested for titanium allergy BEFORE I go thru and pay for a bunch of other tests? Thanks for your help.
Thanks for the question. Have you ever had any sensitivities to metals before? I think it might be worth getting tested before you do any treatment. Tests are minimally invasive and less costly and can give you some good information. I wish you the best!
Hello sir,
I had an implant placed last year in bottom right molar tooth number 30 amd within 2 weeks i had rash all iver back neck and scalp it it hed for months then i developed eye infections as well i have never had and dizziness all the time along with increased anxiety over this. I have tried to find testing for the MELISA but no allergist will order it and half dont know what it is. Any suggestions? Could this be an allergy to the titanium? It was a keystone 7mm implant super wide…o also saw another surgeon who said the implant was alnost to the nerve and was not 1 to 2mm away…how is the recovery of removal? And could it cause further nerve damage?
I’m sorry to hear this. Yes, this could be an allergy. I’m sorry but I don’t have any advice about getting a MELISA test. We have had other patients that have been able to find a way to get one. We are not involved in this.
As far as removing the implant, this really depends on the case. Sometimes the implant will just reverse out and there is really no damage at all but sometimes it can remove bone and tissue when being removed. If it is close to your nerve, there is of course risk in that. I wish you all the best and hope you get the help you need!
Dr. Stanley
Hello sir.
I recieved 4 titanium implant 9 years ago. And I had skin problems with nickel when i was born but not so often but since 2 years now my skin started to rach or hives around my body all over and it keeps changing the area it keeps me up at night with all the itching. Hives and sometimes it go away especially this year i got pregnant and it keeps coming up on different area a the time
How can I fix it?
Thank you
If these skin problems are due to your titanium implants, you would need to remove the implants. However, I would first rule out all other sources AND get tested for titanium sensitivity. It can be costly and invasive to remove implants so you would want to make sure this is the best thing to do. I wish you the best!
Hi,
I had a titanium implant fitted on 16th March to replace a missing front tooth after extraction of tooth root which I was told was fractured & had abscesses (this tooth previously had a metal stump with crown attached which inserted into my root & had given me years of discomfort & I believe ill health). I do not know which metal material the original stump was made of but my general dentist told me it was stainless steel & confiscated it after extraction.
I had the titanium implant fitted by a specialist at the same clinic in the UK which involved some gum surgery to adjacent tooth gum as crown lengthening was necessary to create an even smile of two front teeth. I was given 4 anti biotics & approx six numbing injections before the procedure. All went ok & specialist placed a false tooth (which fits to roof of mouth) in the gap & told to remove at bedtime. The anaesthetic didn’t wear off for 5hrs I then experienced expected pain. I removed the false insert before sleep but thought some stiches had undone as bleeding occured (managed to stop & slept upright all night). The next morning rang the clinic, told to do salt water mouthwashes not to worry it would be fine. The following day I was experiencing pain around gum & my glands in groin were swollen so I took a Panadol painkiller. Awoke 5.30am next morning with diarrhoea & skin rash which continued for three days.
The clinic rang me on the 23rd March to change my review appointment from 7th April to 26th May & I told them my symptoms. They thought I may have been allergic to the anti biotics. I rang the clinic again that week due to migraine but they had closed their doors due to the Coronavirus outbreak & were only taking emergencies. The specialist rang me on 31st to reasure me.
I sent an email & text to the specialist (included photos of mouth & skin rash on arm) on 4th April – still in pain. He dismissed the rash but told me to cut out the bunched up stitches with a pair of small scissors. I have managed to do this but with great difficulty. Over all this time I could not place the false tooth back into the gap due to discomfort.
LuckIly, my friend offered to do my main food shopping for me during this pandemic lockdown. I have worn a mask when taking the dog out (to everyone’s amusement) but thought it was the most sensible thing to do.
The past five days I’ve attempted to place the false tooth in the gap but seem to get throbbing from the implant & still have painful glands in my groin. It is now May 3rd & am concerned that I may be allergic to the titanium implant or it has not taken properly.
Would you suggest allergy testing? Plus due to the current situation regarding the Coronavirus my dental team are reluctant to see patients. Do you know whether implants can be removed after being fixed in for weeks? I have yet to have the abutment & Crown fitted.
Hope you can give me some help/advice on a way forward.
I’m sorry to hear about your experience. Implants are easy to remove before 6 weeks of post-operative time since they will not have integrated yet. After a few months, they can be difficult to remove but it is still possible and case dependant.
After dental implant (titanium) I developed itching, hives on the skin all over my body (mostly the back of my body). dermatologist could not find the couse and concluded “no further treatment needed!!
I went on internet looking for some guidance,
it seems to me that I am allergic to titanium.
Q:1. will this hives will ever go away? What are the prognosis in the similar situation?
Q:2. Is titanium from Germany better than from other country, (seems China, France , Switzerland and the countries are making titanium implants)
With appreciation for your anticipated answer.
It is difficult to tell what will happen. IF you have a true allergy to the materials, I would predict that your situation will not get better. Titanium is titanium no matter where it comes from, however, you need to know what other metals are contained within the titanium used from each company.
I have been trying to find out more about what symptoms are in a little more detail when it comes to titanium implants. I currently have two. A few months after the second one I started getting mouth sores and my hips aches and stiffened up after sitting for a period of time. Since then other joints have experienced pain, mainly elbows, and some in my fingers. My back has a knot in it that did not change after going to a chiropractor. I get occasional headaches and do not have any real pain in my mouth surrounding the implants. I have had extensive tests done for autoimmune diseases and the other standard testing with it all negative. I am wondering if any of this could be related to implants/titanium!!
Hi David- It could be related, but there isn’t any standard reaction I am aware of and I suspect there is a lot of potential variability between different individuals. Mouth sores have been mentioned several times so it seems like a common presentation. I want to be very clear that we have put this information out there to open up the discussion and hear from patients like you, but by no means do we have this all figured out. I believe titanium is well tolerated by an overwhelming majority of patients, but a small percentage of patients are affected adversely because they are either more sensitive or allergic. Even though this is rare, it is still a serious concern and something I am very interested in. To answer your question, it could be related but there is no non-invasive way to be certain so I would urge caution.
Hello sir ,
About 3 months ago i had implant couple hours i felt eye pressure movement pain sometimes, on second follow up appointment he tightened my abutment couple hours i had throbbing pain in cheek bones so doctor did cbct scan tooth behind implant root canal broke and infected so he extracted it second day my nose was pulsating and tingling facial And pressure in head its been going on for 2 months Do you think it’s from implant or extraction? I also went to neurologist and ent and did mri/mra to check on nerve every thing showed normal! I can email you my cbct dental implant before and after too , please help i need second opinion if i need to remove the implant .
Thank you!
Hi Neveen- It could be from the implants, the extraction, or even some unrelated condition. The CBCT imaging before and after could help but sometimes in-person evaluation would be necessary to accurately determine the cause. Even then, sometimes everything looks ok despite symptoms but I think the CBCT imaging could be revealing. If you are interested in a second opinion, we could do a remote consultation. Submit the form here and someone from my team will contact you to arrange the consultation.
Neveen, I have very similar events like you did…. Implant with discomfort… after measurements for abutment, lots of pain in jaw, cheek, eye, ear area…. after abutment placed, same thing… weird! Also had MRI (neurologist) with nothing to show… ugh. I plan on getting the final crown on my implant, because I am tired of no tooth….. Really ironic that you have had similar symptoms as I did… good luck…. I may look locally for a melisa test.
I had 3 titanium teeth implants procedures done in Mexico . 1 in August 2019 and 2 in February 2020. I have been getting ulcers in my mouth often and now I have something going on with my tongue. Swelling, red and a burning soreness. I know all of my life I could never wear costume jewelry because of itchy rashes. Could the implants be causing this problem in my mouth ?
Hi Kimberly- There are a lot of possibilities. I recommend you have this evaluated as soon as possible. It could be the implants, especially if a lower quality or generic type of implant was used which may be the case. There is no benefit in speculating though. Please have this evaluated urgently. I hope your condition improves. All the best – MN
I have been reading your blog Kyle, thank you for all your information.
2 mo. ago I had my implant in lower left jaw,ever since lm experienceing noise in my left, ear it’s a drumming sound ( like my heartbeat) keeps me awake at night,plus I’m starting to get spells of dizziness. If I do have a allerg,how do I connect withGermany to get the MELISA testing.
Judith
I’m sorry to hear you are having this problem. We are not connected to the lab in Germany so you have to call/email them yourself to arrange for the test. We have had patients do this on their own before and get a test. I wish you the best!
Hi Judith:
I saw your post on Dr. Kyle Stanley’s blog. I had a tooth implant at the end of January 2021. Since then I have had the same reaction, drumming sound in ears, dizziness, like you did. I wonder if your problem has resolved and if you found the root cause of it. I am very grateful that I am not the only person with this reaction.
Yuli
I had an implant done 10 years ago. I have constant pain, irritated gums around the tooth with the implant. Extremely dark circles under my eyes that developed after the implant was put in. My lips are always irritated. Many dentists, I say many because I have tried to get it solved and each dentist tries something and sends me on….changed the crown from ceramic to gold, fixed the so called bent abutment, use non-traditional toothpastes and mouth rinses, drugs and still have trouble. I can’t wear cheap earrings or my ears burn from the metal. Any ideas on this?
It sounds like you could be allergic to your implant. The fact that your ears burn from cheap metal makes me think this. You should go to a dentist who really understands this phenomenon. I would also take a MELISA test if I were you. You can go online and find out how to get a test.
Dr Stanley,
I had an dental implant, (titanium), about 4 months ago, and about 2 months ago started having angioedema symptoms, including mouth soreness, lip swelling that comes and goes. I also have fatigue as well as joint pain. My GI doctor cleared me for any GI causes, (I also have Crohn’s), but suggests that I see an oral pathologist since we have been unable to pinpoint the cause of what is now becoming a chronic condition. Since oral pathologists are few and far between, should I see an allergist first? I also have an allergy to nickel and also to Neomycin. Also, is the packing material used in the healing process known to cause any allergic reactions? It was bright blue, resembled a strechy thick dental floss.
Hi Carol, I would recommend you see an oral pathologist as recommended by your GI specialist. Some implants have trace amounts of Nickel. I am unaware of the packing material causing any allergic reactions but if this was 4 months ago, and the membrane has resorbed or been removed, then I would think that the reaction to this would be an unlikely cause since the source is gone. Wishing you all the best- Matt Nejad DDS
Three years ago I had implants inserted into my front upper gum. I’ve had numbness and pressure in my gums and nose ever since. It’s actually getting worse. Also sinus problems.
The odd thing is other implants in my lower left jaw and upper right jaw seem to be ok. Is it possible for rejection to occur in one area of the mouth and not others ?
It would be very unlikely for this to be an allergy. This is probably more based on the positioning of the implant into the nose or sinus. I would get a CT scan and have it evaluated to look for positioning.
Dr Stanley
Hi – I had a dental impant done November 2019, and ever since then I have had an itchy, irritation in my gums, roof of mouth and tongue. Very uncomfortable feeling. Could this be an allergy?
Yes, this could be an allergy. Are you allergic to other types of metals that you know of?
Dr. Stanley
My 66 y/o husband had two upper molars removed with appropriate healing time delay before titanium rods placed. Three weeks post that procedure, l he experienced an eczema outbreak on both hands and significant swelling of both eye lids and facial swelling. Benedryl tempered the swelling. A similar flare occurred 3 more times in the last two months. His general dentist (in NJ) who placed the rods does not acknowledge any connection. Do u suggest consulting an oral surgeon and/ or allergist for a second opinion? Thank you for your input.
I think he should get tested for sure. It could be related.
Dr Stanley
I have Chronic Fatigue and Fibro. I have a dental titanium implant and the Melisa test shows I am allergic to 2 nickel types. I’ve had this implant 15 years and have had progressive CFS. I am planning to get this out. Have you seen people recover from CFS after removal? Is it a nightmare to remove? Number 13 tooth.
Thanks!
Yes, often times you will recover. It can be easy to remove but may require some small bone removal which can be grafted. You should be fine! Good luck!
Hi I recieved a titanium implant 4 months ago. I have never had skin problems and have started to develop all sorts of skin and eye ailments. A rach on my neck all the way to my scalp that has my dermatologist and allergist dumbfounded. It keeps me up at night with all the itching. Hives for no reason randomly appear sometimes then go away. I have no issues at the site of the implant though. So everyone disregards. When I asked for the MSDS sheet to know what exactly was in the implant they did not know what that was. I also have been increasingly dizzy for no reason what so ever. Do you know if these are symptoms and what can be done?
I also had a previous mini implant from 12 years ago have no idea what was in it as it was a different dentist but did not experience and of these symptoms. Can one titanium implant differ from the other in terms of metals used? Any advice greatly appreciated.
Hi Kim- unfortunately there is no one specific combination that is used universally. This type of information really should be included with every implant, but unfortunately is not. In a 2019 study by Chaubey et al., they examined the composition of 5 brands and found varying amounts of: Titanium, Iron, Manganese, Chromium, Tin, Vanadium, Molybdenum, Zirconium, Niobium, Zinc, Tungsten, and Nickel. In a few (3) of the implants tested, Titanium made up over 99% and in the other 2 titanium was 89%. I would recommend further evaluation. The problem is that removing the implant is pretty invasive and its best to evaluate all options beforehand. Some people ultimately elect to remove the implants, though I have seen cases where this improved symptoms as well as cases where symptoms would persist- I recommend a cautious approach. Wishing you all the best- Matt Nejad DDS
What is the turn around time for your MELISA tests? Do you send them to Germany for processing? We are in Texas and deperately trying to find the quickest way to get a MELISA test. My husband had rare surgery at UCLA, and a small titanium plate closes the hole in his craniumHe has extreme fatigue, a rash and a couple of other symptoms. He’s had a lumbar puncture, caraotid arteries checked, every blood test imaginable and CT Scans, chest Xrays, etc. All were good. We researched, and are sure he has Titanium Allergy. We know he needs the MELISA test, and are looking for the quickest way to get it processed. Do you have access to anything quicker than what the MELISA siteoffers online?
Thanks for taking time to respond.
Trish,
I’m sorry to hear about your husband. I do not know the turn around time with MELISA in Germany but you do have to send it to them. Contact them directly and they can give you the turn around time. I hope your husband gets better soon!
Dr. Kyle Stanley
I had eight titanium implants removed 3 weeks ago because they were literally killing me for whatever reason I had some sort of ionic or galvanization or whatever they call it I suffered through 6 months of agonizing pain in every joint bilaterally throughout my whole body I’m almost 100% better now since I had these things removed
Linda,
I’m sorry to hear this. Did you ever have any metal problems before your implant surgery? (sensitivity to copper, lead, jewelry, coins, etc?)
I’m glad to hear you are going better.
Dr. Kyle Stanley
Hi!! Had an implant placed on #28 in May and I too am experiencing joint pain in my knees and also twitching throughout my body, mostly arms and legs. MI thinking of having it removed. Did you experience any twitching?hanks
I would like my upper 2 titanium implants removed as I believe they are causing me to suffer from dizziness & swelling of the face & skin irritation.
Could you suggest a surgeon who could remove them
I live in Ilford London UK
Nearly five years ago my wife received two titanium rods in her lower jaw to secure a full denture. Soon after the implant procedure she began experiencing chronic nausea and other symptoms such as hair loss, fatigue, sinus congestion and eventually weakening of one of the implant rods. She received numerous gastroenterological tests to determine the cause of the nausea, all of which were negative. It was recently suggested she be tested for possible allergic and intolerance reactions to titanium which resulted in a diagnoses of positive sensitivity to the material. She was also found to have an early detection of a malignant lesion on the lower left lobe of her lung which required surgical removal This occurred some four years after the implant procedure. At no time was she screened for allergic sensitivity to titanium prior to the procedure or informed of the possibility of such. The dentist who performed the procedure has now refused to remove the implants or acknowledge any possible connection with the problems my wife has experienced. Are you aware of any similar symptoms associated with titanium dental implants?
Hello John,
I’m sorry to hear about your wife and her symptoms. Most of the commonly occurring symptoms are listed on this blog. Because true titanium allergy is VERY rare, we don’t see a lot of patients with this problem. Most of them are also allergic to nickel and they usually tell the doctor about that. These are patients that can never wear jewelry, metal glasses, etc so it is a large part of their life which they commonly tell their doctors. Although we would never know, I would think that the malignant lesion has nothing to do with the titanium allergy and was a coincidence. The reason we don’t commonly test patients for titanium allergy is that it is so rare. Another thing your wife could be allergic to is the material involved in the restoration (some people are allergic to acrylic). Which type of test did she have to determine her titanium allergy? I wish you and your wife all the best!
Dr. Kyle Stanley